Next-Generation Animal Vaccines for Enhanced Protection

Powered by a Herpesvirus Delivery Platform

Designed for a lifetime of active immunity – even in the presence of maternal antibodies

Partners & Funders

Our network of trusted partners and funders past and present. Working together to build a better future for animal health.

The Vector Platform

Maternal-Antibody Tolerant

Designed to overcome maternal-antibody interference enabling vaccination during the critical early-life window

Plug and Play

Rapid, modular ‘plug and play’ Bacterial Artificial Chromosome (BAC)-based synthetic biology

Durable Immunity

Robust vector designed for sustained immune responses and long lasting protection

DIVA Compatible

Ability to differentiate infected from vaccinated animals (DIVA), supporting surveillance programmes and regulatory acceptance

Our Focus

Targeting high-impact viral and bacterial diseases in livestock, with expansion into selected companion animal diseases. 

Lead Candidate Vaccine Programme

Green icon of a cow silhouette.

Bovine Respiratory Syncytial Virus (BRSV)

Early-life respiratory protection in calves, including in the presence of maternally-derived antibodies (MDA).

Indicative at risk calf populations:

  • UK dairy calves window: ~1.57M/year
  • USA dairy calves window: ~8.2M/year
  • India annual calf crop: 87 to 94M/year

Market Opportunity:

BRSV sits within a significant cattle-health opportunity shaped by two major windows of vulnerability: early life, when maternally-derived antibodies can limit vaccine effectiveness, and post-weaning, when stress and commingling increase disease risk.

TVG’s lead programme is designed to address the early-life protection gap, with clear relevance in major cattle markets such as the UK and USA and broader significance across global livestock systems.

Stage:

  • Proof-of-principle cattle study complete
  • Structured for licensing and co-development with animal health partners

Key Differentiators:

  • Maternal antibody tolerance
  • Designed for early life administration
  • Parenteral administration associated with durable immunity
Cow comforting a calf in an open grass field.

Candidate vaccine programmes are advancing through defined translational milestones towards commercial partnership

To find out more about our candidate vaccine pipeline, click below:

Second Candidate Vaccine Programme

Three small piglets digging in the mud in a grassy field.

Platform Expansion

Grey silhouette illustration of a farmyard.

Livestock

Cattle

Lumpy Skin Disease (LSD)

Bovine tuberculosis (bTB)

Bovine mastitis

Swine

African swine fever (ASF)

Porcine reproductive and respiratory syndrome (PRRS)

Porcine circovirus-2 (PCV2)

Porcine cysticercosis

Grey dog and cat silhouette.

Companion Animals

Canine leishmaniasis

Feline immunodeficiency virus (FIV)

Equine influenza virus (EIV)

Canine oncology

Latest News